Protecting wipes and the baby’s skin – we are up for the challenge!

When we think of the skin microbiome, we wish to avoid disruption of normal skin conditions. It is especially the case when it comes to infant skin. Preservation systems intend to protect the product by preventing microbial contamination. But what about protecting the baby’s skin? With the help of a new wet-wipes preservation system, SharoWIPES™, this can be achieved as well!

A test was conducted to measure the diversity of several microbial species, representing the baby skin microbiome, in the presence of SharoWIPES™ systems.  The results clearly indicate SharoWIPES™ is not harmful to microbiome species, including that of an infant microbiome.

The infant skin and the development of early microbiome

The acquisition of the infant microbiome begins at birth when the baby emerges from the sterile aqueous environment of the uterus to a dry environment colonized by many microorganisms [1]. The microbiota, play a major role in skin barrier function. Despite the higher water content compared with adults, the skin of the newborn is not fully mature, with undeveloped barrier function, characterized by relatively higher water loss rates per unit area [2], and decreased ability to protect against irritant and allergen penetration. In addition, infant epidermal structure is characterized by smaller cells and thinner layers [3].

In the past few years, it is becoming clear that the delivery mode can significantly influence the type of microorganisms colonizing the newborn child in its early days. Vaginally delivered infants will have skin bacteria resembling the mother’s vaginal tract, such as Lactobacillus spp., while the skin microbiome of neonates delivered by cesarean resembles the mother’s skin bacteria, including Staphylococcus, Corynebacterium, and Cutibacterium [4,5].

Within days after birth, significant physiological and functional changes occur in the infant’s skin, along with rapid colonization of microorganisms. Gradually, the diversity of the microbial community increases and becomes site-specific similar to adults [5,6]. Early establishment of diverse and healthy microbial communities on the infant skin is critical for the proper development of the immune system, protecting against diseases such as atopic dermatitis [7].

By: Noa Ziklo, Innovation Group

  1. Perez-Muñoz, M.E.; Arrieta, M.C.; Ramer-Tait, A.E.; Walter, J. A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: Implications for research on the pioneer infant microbiome. Microbiome 2017, 5, 1–19, doi:10.1186/s40168-017-0268-4.
  2. Nikolovski, J.; Stamatas, G.N.; Kollias, N.; Wiegand, B.C. Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life. J. Invest. Dermatol. 2008, 128, 1728–1736, doi:10.1038/sj.jid.5701239.
  3. Stamatas, G.N.; Nikolovski, J.; Luedtke, M.A.; Kollias, N.; Wiegand, B.C. Infant skin microstructure assessed in vivo differs from adult skin in organization and at the cellular level. Pediatr. Dermatol. 2010, 27, 125–131, doi:10.1111/j.1525-1470.2009.00973.x.
  4. Dominguez-Bello, M.G.; Costello, E.K.; Contreras, M.; Magris, M.; Hidalgo, G.; Fierer, N.; Knight, R. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 11971–11975, doi:10.1073/pnas.1002601107.
  5. Luna, P.C. Skin Microbiome as Years Go By. Am. J. Clin. Dermatol. 2020, 21, 12–17, doi:10.1007/s40257-020-00549-5.
  6. Capone, K.A.; Dowd, S.E.; Stamatas, G.N.; Nikolovski, J. Diversity of the human skin microbiome early in life. J. Invest. Dermatol. 2011, 131, 2026–2032, doi:10.1038/jid.2011.168.
  7. Leung, D.Y.M. New insights into atopic dermatitis: Role of skin barrier and immune dysregulation. Allergol. Int. 2013, 62, 151–161, doi:10.2332/allergolint.13-RAI-0564.


The preservation of wet wipes is a challenge. The microbiological risk is due to the unique product characteristics of wipes, which contain both formula & fabric. External factors such as in-use habits are adding to the difficulty, as well as the packaging. Ingredient’s safety concerns are especially high in wipes, as wet wipes are used for baby care and on sensitive areas. The industry is facing another hurdle: a strong trend of “free-from” claims, which are limiting the choice of ingredients and preservation system.

SharoWIPES™ line offers a technological breakthrough by providing a solution that protects both the formula and the non-woven. The systems in the line are composed of a carefully selected combination of hydrophilic elements, together with an anti-biofilm agent.

Ultimate protection for wipe and formula

SharoWIPES™ preservative line shows high efficacy and broad-spectrum protection at a low level of use, the platform is flexible and water-soluble.

Clean label & Eco friendly

SharoWIPES™ preservative line is readily biodegradable, vegan, and free from phenoxyethanol, parabens, CIT/MIT, and formaldehyde donors.

Safety First

SharoWIPES™ preservative line is clinically tested and found suitable for baby wipes and sensitive areas. All components have an E number, as they are listed as food additives.

Contact us to learn more about the activity of SharoWIPES systems in personal care and baby wipes.

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